Substantial rate enhancements of the esterification reaction of phthalic anhydride with methanol at high pressure and using supercritical CO2 as a co-solvent in a glass microreactor.

نویسندگان

  • F Benito-Lopez
  • R M Tiggelaar
  • K Salbut
  • J Huskens
  • R J M Egberink
  • D N Reinhoudt
  • H J G E Gardeniers
  • W Verboom
چکیده

The esterification reaction of phthalic anhydride with methanol was performed at different temperatures in a continuous flow glass microreactor at pressures up to 110 bar and using supercritical CO(2) as a co-solvent. The design is such that supercritical CO(2) can be generated inside the microreactor. Substantial rate enhancements were obtained, viz. a 53-fold increase was obtained at 110 bar and 60 degrees C. Supercritical CO(2) as a co-solvent gave rise to a 5400-fold increase (both with respect to batch experiments at 1 bar at the same temperature).

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عنوان ژورنال:
  • Lab on a chip

دوره 7 10  شماره 

صفحات  -

تاریخ انتشار 2007